منابع مشابه
Hepatic Vitamin B6 Metabolism
nM. Thus, pyridloxal-P is the principal B6 vitaimer in plasma. Durinig pyridoxine stupplemiienitation, mealn plasnma levels of the B6 vitaimers anid pyridoxic acidl increasedl to 655±122 aindl 222±55 nM, respectively. The plasma content of pyridoxal-P aind( pyricloxic acidl increased 6-7-fold anid thatt of pyridoxal, 12-fold, but the pyridloxiine level did niot increase. Isolatedlhepatocytes, 1...
متن کاملVitamin B6 and arteriosclerosis.
In 1949, Rinehart and Greenberg reported that marked arteriosclerosis occurs in vitamin-B6-deficient monkeys. The present study investigates the relationship between vitamin B6 and arteriosclerosis and summarizes the results. I found that thrombogenesis, disorder of collagen metabolism and production of free radicals may be the processes that cause arteriosclerosis in human and experimental ani...
متن کاملPlasma vitamin B6 vitamers before and after oral vitamin B6 treatment: a randomized placebo-controlled study.
BACKGROUND Vitamin B(6) has attracted renewed interest because of its role in homocysteine metabolism and its possible relation to cardiovascular risk. We examined the plasma B(6) vitamers, pyridoxal 5'-phosphate (PLP), pyridoxal (PL), pyridoxine (PN), and 4-pyridoxic acid (4-PA) before and after vitamin B(6) supplementation. METHODS Patients (n = 90; age range, 38-80 years) undergoing corona...
متن کاملEffect of vitamin B6 on Ieucine-induced
Disturbances in the tryptophan-niacin pathway seen in endemic pellagra among sorghum eaters have been ascribed to high dietary intake of leucine. Vitamin B, plays an important role in several steps of this pathway. Therefore, studies on possible metabolic interrelations between excess dietary leucine and vitamin B, were undertaken in normal healthy human subjects. The results indicated that vit...
متن کاملNon-nutritional uses of vitamin B6.
Vitamin B6 is a water-soluble vitamin, and is readily metabolized and excreted, so it has generally been assumed to have negligible toxicity, although at very high levels of intake it can cause peripheral nerve damage. Nutritional deficiency disease is extremely rare, although a significant proportion of the population shows biochemical evidence of inadequate status, despite apparently adequate...
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ژورنال
عنوان ژورنال: Proceedings of the Nutrition Society
سال: 1994
ISSN: 0029-6651,1475-2719
DOI: 10.1079/pns19940071